Areas of specialization

Exercise physiology, pediatrics, obesity, metabolism, vascular biology

Research interests

The focus of my research since 1991 has revolved around the metabolic syndrome and lifestyle modification as a treatment of this metabolic condition. My initial studies examined the effects of weight loss and physical activity on carbohydrate metabolism and older, obese hypertensive individuals. Recently, my research has focused on the metabolic syndrome in overweight children and adolescents. Although the metabolic syndrome is thought to be due to the development of obesity that occurs during aging, we have discovered an increasing number of obese children that are displaying similar characteristics of this disease. I am currently are conducting a series of studies that are examining blood vessel structure and function and the metabolic syndrome in overweight and obese children before and after lifestyle modifications such as: aerobic exercise training, weight loss and resistance training. [Read more at "Saving Young Hearts".]

In addition to our recent studies in overweight and obese children, I have begun to examine blood vessel structure and function and the metabolic syndrome in adult survivors of childhood acute lymphoblastic leukemia. Although these individuals are cancer free they develop a number of metabolic conditions associated with the metabolic syndrome. These studies will be expanded to examine child (ages 8-18 yrs) survivors of various forms of cancer and the effect of their cancer treatments on blood vessel structure and function.

Education

• 1990-1994, National Institute of Aging Postdoctoral Research Fellow, Division of Gerontology, University of Maryland School of Medicine, Baltimore, Maryland (Laboratories of Drs. Andrew P. Goldberg and James M. Hagberg); post-doctoral training
• 1987-1990, University of Georgia, Athens, Georgia; Ph.D. (exercise/applied physiology)
• 1984-1986, Ball State University, Muncie, Indiana; M.A. (exercise/applied physiology)
• 1979-1984, University of Wisconsin, LaCrosse, Wisconsin; B.S. (magna cum laude, honors in physical education)
• 1979-1984, University of Wisconsin, LaCrosse, Wisconsin; B.S. (magna cum laude, honors in health education)

Selected works

Dengel DR, Pratley RE, Hagberg JM, Rogus EM, Goldberg AP: Distinct effects of aerobic exercise training and weight loss on glucose homeostasis in obese sedentary men. Journal of Applied Physiology 81:318-325, 1996.

Dengel DR, Galecki AT, Hagberg JM, Pratley RE:  The independent and combined effects of weight loss and aerobic exercise on blood pressure and oral glucose tolerance in older men. American Journal of Hypertension 11:1405-1412, 1998.

Dengel DR, Brown MD, Ferrell RE, Reynolds TH, Supiano MA: Exercise-induced enhancements in insulin action are associated with ACE gene polymorphisms in older hypertensives. Physiological Genomics 11:73-80, 2002.

Kelly AS, Wetzsteon RJ, Kaiser DR, Steinberger J, Bank AJ, Dengel DR: Inflammation, insulin, and endothelial function in overweight children and adolescents: the role of exercise. Journal of Pediatrics 145(6):731-736, 2004.

Dengel DR, Ness KK, Glasser SP, Williamson EB, Baker KS, Gurney JG:  Endothelial Function In Young Adult Survivors Of Childhood Acute Lymphoblastic Leukemia.  Journal of Pediatric Hematology Oncology 30:20-25, 2008.

Academic appointments

• 2009-present, Director, Human Performance Core, Clinical and Translational Science Institute, University of Minnesota
• 2007-present, Member, Cancer Center, University of Minnesota
• 2007-present, Senior Member, Nutrition Graduate Program, University of Minnesota
• 2006-present, Adjunct Associate Professor, Department of Pediatrics, University of Minnesota
• 2003-present, co-director, Body Composition Human Performance, General Clinical Research Center, University of Minnesota
• 2003-present, Associate Professor, School of Kinesiology, University of Minnesota
• 2000-2003, Assistant Professor, School of Kinesiology, University of Minnesota
• 2000-present, Research Scientist, Research Service, Minneapolis VAMC
• 1996-2000, Faculty Associate, Institute of Gerontology, University of Michigan
• 1995-2000, Assistant Research Scientist, Department of Internal Medicine, University of Michigan
• 1995-2000, Adjunct Assistant Professor, Division of Kinesiology, University of Michigan
• 1995-2000, Research Scientist, Geriatric Research Education and Clinical Center, Ann Arbor VA Medical Center
• 1994-1995, research associate, Division of Gerontology, University of Maryland School of Medicine

Honors and awards

• 2008, Fellow, American Heart Association, Council on Nutrition, Physical Activity and Metabolism
• 1997, New Investigator Award, American College of Sports Medicine
• 1994, Fellow, American College of Sports Medicine
• 1991, National Research Service Award from NIH (NRSA)
• 1984, Magna Cum Laude, University of Wisconsin-La Crosse
• 1983, Sigma Zeta National Science Honor Society

Research activities

Bibliography

Peer-reviewed publications

Bosch TA, Kaufman CL, Williamson EB, Duprez DA, Dengel DR: Comparison of changes in heart rate variability and blood pressure during nitroglycerin administration and head-up tilt testing. Clinical Autonomic Research 19:46-50, 2009.

Olson TP, Tracy J, Dengel DR: Relationship between ventilatory threshold and cerebral blood flow during maximal exercise in humans. Open Sports Medicine Journal 3:9-13, 2009.

Thomas IH, Donohue JE, Ness KK, Dengel DR, Baker KS, Gurney JG: Bone mineral density in young adult survivors of acute lymphoblastic leukemia. Cancer 113:3248-3256, 2008.

Williamson EB, Bronas UG, Dengel DR: Automated edge detection versus manual edge measurement in analysis of brachial artery reactivity: a comparison study. Ultrasound in Medicine and Biology 34:1499-1503, 2008.

Thelen MA, Kelly AS, Williamson EB, Dengel DR: Examining the time course of endothelium -independent dilation by nitroglycerin. Ultrasound in Medicine and Biology 34:1217-1220, 2008.

Kaufman CL, Kaiser DR, Kelly AS, Dengel JL, Steinberger J, Dengel DR: Diet revision in overweight children: Effect on autonomic and vascular function. Clinical Autonomic Research 18:105-108, 2008.

Olson TP, Tracy JE, Dengel DR: Validity of a low-flow pneumotach and portable metabolic measurement system. Open Sports Medicine Journal 2:23-27, 2008.

Dengel DR, Ness KK, Glasser SP, Williamson EB, Baker KS, Gurney JG: Endothelial Function In Young Adult Survivors Of Childhood Acute Lymphoblastic Leukemia. Journal of Pediatric Hematology Oncology 30:20-25, 2008.

Dengel DR, Brown MD, Ferrell RE, Reynolds TH, Supiano MA: Renal hemodynamic and blood pressure responses to dietary sodium are associated with the t-786c endothelial nitric oxide synthase gene. Physiological Research 56:393-401, 2007.

Ness KK, Baker KS, Dengel DR, Youngren N, Sibley S, Mertens AC, Gurney JG: Body composition, muscle strength deficits, and mobility limitations in adult survivors of childhood acute lymphoblastic leukemia. Pediatric Blood & Cancer 49:975-981, 2007.

Borer KT, Fogleman K, Gross MM, La New JM, Dengel DR: Walking intensity for postmenopausal bone mineral preservation and accrual. Bone 41:713-721, 2007.

Huck CJ, Bronas UG, Williamson EB, Draheim CC, Duprez DA, Dengel DR: Noninvasive measurements of arterial stiffness: Repeatability and interrelationships with endothelial function and arterial morphology measures. Journal of Vascular Health 3(3):343-349, 2007.

Olson TP, Dengel DR, Leon AS, Schmitz KH: I Changes in inflammatory biomarkers following one-year of moderate resistance training in overweight women. International Journal of Obesity 31:996-1003, 2007.

Kaufman CL, Kaiser DR, Steinberger J, Dengel DR: Relationships between heart rate variability, vascular function, and adiposity in children. Clinical Autonomic Research 17(3):165-171, 2007.

Kelly AS, Steinberger J, Olson TP, Dengel DR. In the absence of weight loss, exercise training does not improve adipokines or oxidative stress in overweight children. Metabolism 56:1005-1009, 2007.

Kaufman C, Kelly AS, Kaiser DR, Steinberger J, Dengel DR: Aerobic-exercise training improves ventilatory efficiency in overweight children. Pediatric Exercise Science 19:82-92, 2007.

Reynolds TH, Supiano MA, Dengel DR: Differences in Glucose Clearance: The effects of insulin and resistance training on arm and leg glucose clearance in older hypertensive individuals. Journal of Applied Physiology 102:985-991, 2007.

Dengel DR, Kelly AS, Steinberger J, Sinaiko AR: Effect of oral glucose loading on endothelial function in normal and overweight children. Clinical Science 112(9):493-498, 2007.

Parker ED, Schmitz KH, Jacobs DR, Dengel DR, Schreiner PJ: Physical activity in young adults and incident hypertension over 15 years of follow-up: The CARDIA study. American Journal of Public Health 97:703-709, 2007.

Kaufman CL, Kaiser DR, Steinberger J, Kelly AS, Dengel DR: Relationships of Cardiac Autonomic Function with Metabolic Abnormalities in Childhood Obesity. Obesity 15:1164-1171, 2007.

Scott RM, Kaufman CL, Dengel DR: The Impact of Chiropractic Adjustments on Intracranial Blood Flow: A Pilot Study. Journal of Vertebral Subluxation Research 1-8, May 21, 2007.

Van Guilder GP, Hoetzer GL, Dengel DR, Stauffer BL, DeSouza CA: Impaired endothelium-dependent vasodilation in normotensive and normoglycemic obese adult humans. Journal of Cardiovascular Pharmacology 47:310-313, 2006.

Dengel DR, Brown MD, Reynolds TH, Supiano MA: Effect of aerobic exercise training on renal responses to sodium in hypertensives. Medicine and Science in Sports and Exercise 38:217-222, 2006.

Dengel DR, Brown MD, Reynolds TH, Kuskowski MA, Supiano MA: Effect of aerobic exercise training on blood pressure sensitivity to dietary sodium in older hypertensives. Journal of Human Hypertension 20:372-378, 2006.

Olson TP, Schmitz KH, Leon AS, Dengel DR: Vascular structure and function in women: relationship with body mass index. American Journal of Preventive Medicine 30:487-492, 2006.

Dengel DR, Kelly AS, Olson TP, Kaiser DR, Dengel JL, Bank AJ: Effects of weight loss on insulin sensitivity and arterial stiffness in overweight adults. Metabolism 55:907-911, 2006.

Gurney JG, Ness KK, Sibley SD, O'Leary M, Dengel DR, Lee JM, Youngren NM, Glasser SP, Baker KS: Metabolic syndrome and growth hormone deficiency in adult survivors of childhood acute lymphoblastic leukemia. Cancer 107(6):1303-1312, 2006.

Olson TP, Dengel DR, Leon AS, Schmitz KH: Moderate resistance training and vascular health in overweight women. Medicine and Science in Sports and Exercise 38(9): 1558-1564, 2006.

Kelly AS, Steinberger J, Kaiser DR, Olson TP, Bank AJ, Dengel DR. Oxidative stress and adverse adipokine profile characterize the metabolic syndrome in children. The Journal of Cardiometabolic Syndrome 1:248-252, 2006.

Lee C, Glickman SG, Dengel DR, Brown MD, Supiano MA: Abdominal adiposity assessed by dual energy X-ray absorptiometry provides a sex-independent predictor of insulin sensitivity in older adults. Journal of Gerontology: Medical Sciences 60A:872-877, 2005.

Reynolds TH, Reid P, Larkin LM, Dengel DR: Effects of aerobic exercise training on the protein kinase B (PKB)/mammalian target of rapamycin (mTOR) signaling pathway in aged skeletal muscle. Experimental Gerontology 39: 379-385, 2004.

Reynolds TH, Supiano MA, Dengel DR: Resistance training enhances insulin-mediated glucose disposal with minimal effect on the tumor necrosis factor-alpha system in older hypertensives. Metabolism 53(3):397-402, 2004.

Glickman SG, Marn CS, Supiano MA, Dengel DR: Validity and reliability of dual-energy X-ray absorptiometry for the assessment of abdominal adiposity. Journal of Applied Physiology 97:509-514, 2004.

Kelly AS, Wetzsteon RJ, Kaiser DR, Steinberger J, Bank AJ, Dengel DR: Inflammation, insulin, and endothelial function in overweight children and adolescents: the role of exercise. Journal of Pediatrics 145(6):731-736, 2004.

Kelly AS, Kaiser DR, Dengel DR, Bank AJ: Comparison of B-mode and echo-tracking methods of assessing flow-mediated dilation. Ultrasound in Medicine and Biology 30(11):1447-1449, 2004.

Kelly AS, Wetzsteon RJ, Kaiser DR, Steinberger J, Bank AJ, Dengel DR: Inflammation, insulin, and endothelial function in overweight children and adolescents: the role of exercise. Journal of Pediatrics 145(6):731-736, 2004.

Glickman SG, Marn CS, Mark A. Supiano MA, Dengel DR: Validity and reliability of dual-energy X-ray absorptiometry for the assessment of abdominal adiposity. Journal of Applied Physiology 97:509-514, 2004.

Reynolds TH, Supiano MA, Dengel DR: Resistance training enhances insulin-mediated glucose disposal with minimal effect on the tumor necrosis factor-alpha system in older hypertensives. Metabolism 53(3):397-402, 2004.

Reynolds TH, Pamela Reid P, Larkin LM, Dengel DR: Effects of aerobic exercise training on the protein kinase B (PKB)/mammalian target of rapamycin (mTOR) signaling pathway in aged skeletal muscle. Experimental Gerontology 39: 379-385, 2004.

Alexander NB, Dengel DR, Olson RJ, Krajewski KM: Oxygen uptake (VO2) kinetics and functional mobility performance in impaired older adults. Journal of Gerontology: Biological Sciences 58A(8):734-739, 2003.

Dengel DR, Brown MD, Ferrell RE, Reynolds TH, Supiano MA: Exercise-induced enhancements in insulin action are associated with ACE gene polymorphisms in older hypertensives. Physiological Genomics 11:73-80, 2002.

Reynolds TH, Krajewski KM, Larkin LM, Reid P, Halter JB, Supiano MA, Dengel DR: Effect of age on skeletal muscle proteolysis in extensor digitorum longus muscles of B6C3F1 mice. Journal of Gerontology: Biological Sciences 57A:B198-B201, 2002.

Brown MD, Dengel DR, Hogikyan RV, Supiano MA: Sympathetic activity and the heterogeneous blood pressure response to exercise training in hypertensives. Journal of Applied Physiology 92:1434-1442, 2002

Dengel DR, Brown MD, Ferrell RE, Supiano MA: Role of angiotensin converting enzyme genotype in sodium sensitivity in older hypertensives. American Journal of Hypertension 14:1178-1184, 2001.

Pratley RE, Hagberg JM, Dengel DR, Muller DC, Rogus EM, Goldberg AP: Aerobic exercise training-induced reductions in abdominal fat and glucose stimulated insulin responses in middle-aged and older men. Journal of American Geriatrics Society 9:1055-1061, 2000.

Brown MD, Hogikyan RV, Dengel DR, Supiano MA: Sodium-sensitive hypertension is not  associated with higher sympathetic nervous system activity in older hypertensive humans. American Journal of Hypertension. 13:873-883, 2000.

Feely RS, Larkin LM, Halter JB, Dengel DR: Chemical vs. dual energy X-ray absorptiometry for detecting age-associated body compositional changes in male rats. Experimental Gerontology 13:417-427, 2000.

Taylor-Tolbert NS, Dengel DR, Brown MD, McCole SD, Pratley RE, Ferrell RE, Hagberg JM: Ambulatory blood pressure after acute exercise in older men with essential hypertension. American Journal of Hypertension 13(1):44-51, 2000.

Brown MD, Srininvasan M, Hogikyan RV, Dengel DR, Glickman SG, Galecki A, Supiano MA: Nitric oxide biomarkers increase during exercise-induced vasodilatation in the forearm. International Journal of Sports Medicine 21:83-89, 2000.

Hagberg JM, Ferrell RE, Dengel DR, Wilund KR: Exercise training-induced blood pressure and plasma lipid improvements may be genotype dependent. Hypertension 34:18-23, 1999.

Hagberg JM, Ferrell RE, Katzel LI, Dengel DR, Sorkin JD, Goldberg AP: Apolipoprotein E , genotype and exercise training-induced increases in plasma high-density lipoprotein (HDL)- and HDL2-cholesterol levels in overweight men. Metabolism 48(8):943-945, 1999.

Dengel DR, Hogikyan RV, Brown MD, Glickman SG, Supiano MA: Insulin sensitivity is , associated with blood pressure response to sodium in older hypertensives. American Journal of Physiology 274(37):E403-E409, 1998.

Dengel DR, Hagberg JM, Pratley RE, Rogus EM, Goldberg AP: Improvements in blood pressure, glucose metabolism, and lipoprotein lipids after aerobic exercise plus weight loss inobese, hypertensive middle-aged men. Metabolism 47:1075-1082, 1998.

Dengel DR, Galecki AT, Hagberg JM, Pratley RE: The independent and combined effects ofweight loss and aerobic exercise on blood pressure and oral glucose tolerance in older men. American Journal of Hypertension 11:1405-1412, 1998.

Macko RF, DeSouza CA, Tretter LD, Silver KH, Smith GV, Anderson PA, Tomoyaus N, Gorman P, Dengel DR: Treadmill aerobic exercise training reduces the energy expenditure and cardiovascular demands of hemiparetic gait in chronic stroke patients. Stroke 28:326-330, 1997.

Macko RF, Katzel LI, Yataco A, Tretter LD, DeSouza CA, Dengel DR, Smith GV, Silver KH. Low velocity graded treadmill stress testing in hemiparetic stroke patients. Stroke 28:988-993, 1997.

DeSouza CA, Dengel DR, Rogers MA, Cox K, Macko RF: Fibrinolytic responses to acute physical activity in older hypertensive men. Journal of Applied Physiology 82(6): 1765-1770, 1997.

Dengel DR, Mayuga RS, Kairis GM, Goldberg AP, and Weir MR. Effect of dietary sodium on insulin sensitivity in middle-aged, obese, sedentary hypertensives. American Journal of Hypertension 10 (Part I):964-970, 1997.

DeSouza CA, Dengel DR, Macko RF, Cox K, Seals DR: Elevated levels of circulation cell adhesion molecules in uncomplicated essential hypertension. American Journal of Hypertension 10:1335-1341, 1997.

DeSouza CA, Dengel DR, Rogers MA, Cox K, Macko RF: The fibrinolytic system is not impaired in older men with hypertension. Hypertension 27:1053-1058, 1996.

Dengel DR, Goldberg AP, Mayuga RS, Kairis GM, Weir MR: Insulin resistance, elevated glomerular filtration fraction and renal injury. Hypertension 28:127-132, 1996.

Dengel DR, Pratley RE, Hagberg JM, Rogus EM, Goldberg AP: Distinct effects of aerobic exercise training and weight loss on glucose homeostasis in obese sedentary men. Journal of Applied Physiology 81:318-325, 1996.

Weir MR, Dengel DR, Behrens MT, Goldberg AP: Salt-induced increases in systolic blood pressure affect renal hemodynamics and proteinuria. Hypertension 25:1339-1344, 1995.

Dengel DR, Pratley RE, Hagberg JM, Goldberg AP: Impaired insulin sensitivity and maximal responsiveness in older hypertensives. Hypertension 23:320-324, 1994.

Dengel DR, Hagberg JM, Coon PJ, Drinkwater DT, Goldberg AP: Effects of weight loss by diet alone or combined with aerobic exercise on body composition in older obese men. Metabolism 43:867-871, 1994.

Dengel DR, Hagberg JM, Coon PJ, Drinkwater DT, Goldberg AP: Effects of hypocaloric diet therapy with and without aerobic exercise on body fat distribution patterns in older obese men. Medicine and Science in Sports and Exercise 26:1307-1315, 1994.

Dengel DR, Weyand PG, Black DM, Cureton KJ: Effects of hypohydration on ratings of perceived exertion at the lactate and ventilatory thresholds. International Journal of Sports Nutrition 3:376-386, 1993.

Lewis RD, Johnson MA, Dengel DR, Jones MT, Norton KI: The effects of maternal training on plasma copper, magnesium and zinc rats. Nutrition Research 13:771-778, 1993.

Dengel DR, Weyand PG, Black DM, Cureton KJ: Effect of varying levels of hypohydration on responses during submaximal cycling. Medicine and Science in Sports and Exercise 24:1096-1101, 1992.

Conley DS, Cureton KJ, Dengel DR, Weyand PG: Validation of the 12-min swim as a field test of peak aerobic power in young men. Medicine and Science in Sports and Exercise 23:766-773, 1991.

Chapters in books

Dengel DR, Reynolds TH: Diabetes. In: LeMura LM and von Duvillard SP (eds), Clinical Exercise Physiology: Application and Physiological Principles. Baltimore, MD: Lippincott, Williams and Wilkins, pp. 319-329, 2004.

Goldberg AP, Hagberg JM, Dengel DR: Exercise physiology and aging. In: Schneider EL and, Rowe JW (eds.), Handbook of The Biology of Aging. 4th edition. New York: Academic Press, Inc. pp. 331-354, 1996.

Dengel DR, Kearney JT, Fleck SJ: Performer readiness for amateur boxing. In: King LA (ed.), Safety Awareness Manual of the USA Amateur Boxing Federation. Colorado Springs, CO: USA Amateur Boxing Federation, pp. 31-43, 1989.

Monographs

Dibner RD, Shubin MM, Taylor-Tolbert N, Dengel DR, McCole SD, Brown MD, Hagberg JM: Effect of exercise training and acute exercise on essential hypertensives. In: Rogozkin VA, Maughan R (eds.), Current Research in Sports Science: An International Perspective. New York: Plenum Press, pp. 295-301, 1996.

Van Handel PJ, Dengel DR, Kearney JT, Bradley PW: A valid and reliable method for sampling blood lactate under field or laboratory condi¬tions. In: Tenenbaum G, Eiger D (eds.), Proceedings of The Maccabiah-Wingate International Congress. Tel-Aviv, Israel: The Emmanuel Gill Publishing House, pp. 38-47, 1990.

Grant support

Current

National Institute of Health, "Evaluating Innovative Weight Gain Prevention Strategies for At-Risk College Students"; Co- Principal Investigator, 2009-2014 (approximately $2,466,074 direct costs)

Department of Veterans Affairs, "Fatigue and Physical Activity in Symptomatic Leg Osteoarthritis"; Co-Investigator, 2008-2011 (approximately $740,200 direct costs)

Lupus Foundation of Minnesota, "Oxidative Stress and Endothelial Function in SLE"; Co-Investigator, 2008-2009 (approximately $35,000 direct costs)

National Institutes of Health, "Cardiovascular Risk and Insulin Resistance: Age 7-40"; Co-Investigator, 2007-2011 (approximately $3,738,228)

National Institute of Health, "Metabolic Syndrome in Childhood Cancer Survivors"; Co-Investigator, 2006-2011 (approximately $3,610,747 direct costs)

National Institute of Health, "Metabolic Syndrome Following Transplant for Leukemia"; Co-Investigator, 2006-2011 (approximately $1,314,179 direct costs)

National Institute of Health, "Etiology of Childhood Obesity (ECHO) Study", Co-Investigator, 2006-2011 (approximately $2,483,956 direct costs)

National Cancer Institute, University of Minnesota TREC Center, "Biological Determinants of Obesity in Teens"; Principal Investigator, 2006-2009 (approximately $100,000 direct costs)

National Cancer Institute, "Examining the Obesity Epidemic through Youth, Family, and Young Adults"; Co-Investigator, 2005-2010 (approximately $7,500,000 direct costs)

USDA, "Preventing Age-Related Weight Gain in Midlife Women"; Co-Investigator, 2007-2010 (approximately $937,722 direct costs)

Recent

Department of Veterans Affairs, "Aerobic Performance, Mobility Limitations and Exercise in Older Adults with Diabetes"; Co-Investigator, 2005-2008 (approximately $701, 053 direct costs)

National Institute of Health, "Influence of Insulin on BP Change During Adolescence"; Co-Investigators, 2004-2008 (approximately $2,500,000 direct costs)

Department of Veterans Affairs, "Functional Circuit Training in Older Adults with Congestive Heart Failure", Co-Investigator, 2003-2007 (approximately $711,600 direct costs)

American Heart Association, "Dietary Composition and Exercise Tolerance in Obese Adults"; Co-Investigator, 2004-2007 (approximately $260,000 direct costs)

National Institute of Health, "Metabolic Syndrome in Adult Survivors of Childhood ALL"; Co-Investigator, 2004-2006 (approximately $250,000 direct costs)

National Institute of Health, "Predicting Energy Balance in Midlife Women"; Co-Investigator, 2005-2006 (approximately $281,846 direct costs)

National Multiple Sclerosis Society, "Effects of a Home-based Aerobic Exercise Program for Persons with Multiple Sclerosis"; Co-Investigator, 2005-2006 (approximately $44,000 direct costs)

Minnesota Obesity Center, "The Effects of Aerobic Exercise on Vascular Structure and Function in Obese Children"; Co-Investigator, 2002-2005 (approximately $40,000 direct costs)

University of Minnesota, "Effects of High Carbohydrate Drinks on Vascular Function in Adolescents"; Principal Investigator, 2002-2004 (approximately $24,191 direct costs)

American Heart Association, "Effects of Exercise Training on Vascular Endothelial Function and Inflammation in Obese Children and Adolescents"; Sponsor, 2002-2004 (approximately $41,000 direct costs)

Department of Veterans Affairs, "Oxygen Kinetics, Mobility Task Performance, and Task Training in Older Adults"; Co-Investigator, 1999-2003 (approximately $540,400 direct costs)

National Institute of Aging/Claude D. Pepper Pilot Grant, "Effects of Age and Exercise Training on Skeletal Muscle Protein Turnover"; Principal Investigator, 1999-2000 (approximately $25,000 direct costs)

Department of Veterans Affairs, "The Effects of Age and Insulin on Protein Turnover"; Principal Investigator, 1999-2000 (approximately $15,000 direct costs)

National Institute of Aging/National Institute of Health (SERCA), "Insulin Action, Sodium and Exercise in the Hypertension of Aging"; Principal Investigator, 1995-2000 (approximately $445,000 direct costs)

University of Michigan - Spring/Summer Research Grant, "Insulin Action, Sodium and Exercise in the Hypertension of Aging"; Principal Investigator, 1997(approximately $2,000 direct cost)

College of Health and Human Performance Research Grant, University of Maryland College Park, MD, "Effect of Acute Exercise on Fibrinolytic Variables in Older Hypertensives"; Co-Investigator, 1994-1995 (approximately $6,000 direct cost)

National Institute of Aging/Claude D. Pepper Pilot Grant, "Effects of Exercise on Blood Pressure and Hyperinsulinemia and Renal Function in the Elderly"; Principal Investigator, 1994-1995 (approximately $12,000 direct cost)

National Institute of Aging/Claude D. Pepper, "Older American Independence Center"; Co-Investigator, 1994-1999 (approximately $5,597,990 direct cost)

Maryland Affiliated-American Heart Association, "Exercise, Insulin and Sodium in Black Hypertensives"; Co-Investigator, 1994-1996 (approximately $22,000 direct cost)

National Institute of Aging, Geriatric Leadership Academic Award Grant, Pilot Grant, "Insulin Action, Sodium and Exercise in Hypertension"; Principal Investigator, 1994-1995 (approximately $5,000 direct cost)

Department of Veterans Affairs, "Geriatric Research, Education and Clinical Center (GRECC)"; Co-Investigator, 1992-1995 approximately $2,345,454 direct cost)

National Institute of Aging, National Research Service Award, "Exercise, Blood Pressure and Metabolism in the Elderly"; Principal Investigator, 1991-1994 (approximately $291,600 direct cost)

Findlay, INC., "Prediction of Oxygen Uptake and Caloric Expenditure from the Findlay Road Machine"; Principal Investigator, 1988-1989 (approximately $1,500 direct cost)

Pending

Department of Defense, ""Effects of Time and Changes in Physical Activity on Vasculature Structure and Function in Adult Survivors of Childhood Cancer", Principal Investigator, 2010-2013 (approximately $1,066,640 direct costs)

National Institute of Health, "Brain and Cognitive Abnormalities in Adolescence Obesity", Co-Investigator, 2009-2014 (approximately $3,468,906 direct costs)

National Institute of Health, "Is Counseling Cost-Effective to Promote Walking for Peripheral Arterial Disease?", Co-Investigator, 2009-2011 (approximately $999,865 direct costs)

National Institute of Health, "Effect of Exercise on Brain and Cognition during Recovery", Co-Investigator, 2009-2014 (approximately $3,323,394 direct costs)

USDA, "Personality and Preventing Excess Weight Gain in Young Adults"; Co-Investigator, 2010-2014 (approximately $ $1,372,399 direct costs)

National Institute of Health, "Hyperinsulinemia & Vascular Function In Late Adolescents: Effects of Exercise"; Principal Investigator, 2010-2015 (approximately $1,855,378 direct costs)

National Institute of Health, "Minnesota Obesity Prevention Training"; Co-Investigator, 2009-2014 (approximately $2,466,074 direct costs)

National Cancer Institute, "Effects of Time & Exercise On Vasculature Of Adult Survivors Of Childhood Cancer"; Principal Investigator, 2009-2014 (approximately $1,250,000 direct costs)

Complete vitae [.pdf]

Revised August 2009