Donald Dengel, PhD

Dengel

Professor


Areas of Interest

Exercise physiology, pediatrics, obesity, metabolism, vascular biology, exercise biochemistry

Graduate education faculty

Director, Laboratory of Integrative Human Physiology

Member, Cancer Center, University of Minnesota

Senior Member, Nutrition Graduate Program

Adjunct Associate Professor, Department of Pediatrics

School of Kinesiology

Room 141B Mariucci Arena
1901 4th St SE
Minneapolis, MN 55414

Tel: 612-626-9701

Fax: 612-625-8867

Curriculum Vitae


Degrees

  • 1990-1994, National Institute of Aging Postdoctoral Research Fellow, Division of Gerontology, University of Maryland School of Medicine, Baltimore, Maryland (Laboratories of Drs. Andrew P. Goldberg and James M. Hagberg); post-doctoral training
  • 1987-1990, University of Georgia, Athens, Georgia; Ph.D. (exercise/applied physiology)
  • 1984-1986, Ball State University, Muncie, Indiana; M.A. (exercise/applied physiology)
  • 1979-1984, University of Wisconsin, LaCrosse, Wisconsin; B.S. (magna cum laude, honors in physical education)
  • 1979-1984, University of Wisconsin, LaCrosse, Wisconsin; B.S. (magna cum laude, honors in health education)

Research interests

The focus of my research since 1991 has revolved around the metabolic syndrome and lifestyle modification as a treatment of this metabolic condition. My initial studies examined the effects of weight loss and physical activity on carbohydrate metabolism and older, obese hypertensive individuals. Recently, my research has focused on the metabolic syndrome in overweight children and adolescents. Although the metabolic syndrome is thought to be due to the development of obesity that occurs during aging, we have discovered an increasing number of obese children that are displaying similar characteristics of this disease. I am currently are conducting a series of studies that are examining blood vessel structure and function and the metabolic syndrome in overweight and obese children before and after lifestyle modifications such as: aerobic exercise training, weight loss and resistance training. [Read more at "Saving Young Hearts"]

In addition to our recent studies in overweight and obese children, I have begun to examine blood vessel structure and function and the metabolic syndrome in adult survivors of childhood acute lymphoblastic leukemia. Although these individuals are cancer free they develop a number of metabolic conditions associated with the metabolic syndrome. These studies will be expanded to examine child (ages 8-18 yrs) survivors of various forms of cancer and the effect of their cancer treatments on blood vessel structure and function.

Academic appointments

  • 2009-present, Director, Human Performance Core, Clinical and Translational Science Institute, University of Minnesota
  • 2007-present, Member, Cancer Center, University of Minnesota
  • 2007-present, Senior Member, Nutrition Graduate Program, University of Minnesota
  • 2006-present, Adjunct Associate Professor, Department of Pediatrics, University of Minnesota
  • 2003-present, co-director, Body Composition Human Performance, General Clinical Research Center, University of Minnesota
  • 2003-present, Associate Professor, School of Kinesiology, University of Minnesota
  • 2000-2003, Assistant Professor, School of Kinesiology, University of Minnesota
  • 2000-present, Research Scientist, Research Service, Minneapolis VAMC
  • 1996-2000, Faculty Associate, Institute of Gerontology, University of Michigan
  • 1995-2000, Assistant Research Scientist, Department of Internal Medicine, University of Michigan
  • 1995-2000, Adjunct Assistant Professor, Division of Kinesiology, University of Michigan
  • 1995-2000, Research Scientist, Geriatric Research Education and Clinical Center, Ann Arbor VA Medical Center
  • 1994-1995, research associate, Division of Gerontology, University of Maryland School of Medicine

Honors and awards

  • 2008, Fellow, American Heart Association, Council on Nutrition, Physical Activity and Metabolism
  • 1997, New Investigator Award, American College of Sports Medicine
  • 1994, Fellow, American College of Sports Medicine
  • 1991, National Research Service Award from NIH (NRSA)
  • 1984, Magna Cum Laude, University of Wisconsin-La Crosse
  • 1983, Sigma Zeta National Science Honor Society

 

Selected Publications

  1.  

    Research activities

    Bibliography

    Peer-reviewed publications

    Bosch TA, Kaufman CL, Williamson EB, Duprez DA, Dengel DR: Comparison of changes in heart rate variability and blood pressure during nitroglycerin administration and head-up tilt testing. Clinical Autonomic Research 19:46-50, 2009.

    Olson TP, Tracy J, Dengel DR: Relationship between ventilatory threshold and cerebral blood flow during maximal exercise in humans. Open Sports Medicine Journal 3:9-13, 2009.

    Thomas IH, Donohue JE, Ness KK, Dengel DR, Baker KS, Gurney JG: Bone mineral density in young adult survivors of acute lymphoblastic leukemia. Cancer 113:3248-3256, 2008.

    Williamson EB, Bronas UG, Dengel DR: Automated edge detection versus manual edge measurement in analysis of brachial artery reactivity: a comparison study. Ultrasound in Medicine and Biology 34:1499-1503, 2008.

    Thelen MA, Kelly AS, Williamson EB, Dengel DR: Examining the time course of endothelium -independent dilation by nitroglycerin. Ultrasound in Medicine and Biology 34:1217-1220, 2008.

    Kaufman CL, Kaiser DR, Kelly AS, Dengel JL, Steinberger J, Dengel DR: Diet revision in overweight children: Effect on autonomic and vascular function. Clinical Autonomic Research 18:105-108, 2008.

    Olson TP, Tracy JE, Dengel DR: Validity of a low-flow pneumotach and portable metabolic measurement system. Open Sports Medicine Journal 2:23-27, 2008.

    Dengel DR, Ness KK, Glasser SP, Williamson EB, Baker KS, Gurney JG: Endothelial Function In Young Adult Survivors Of Childhood Acute Lymphoblastic Leukemia. Journal of Pediatric Hematology Oncology 30:20-25, 2008.

    Dengel DR, Brown MD, Ferrell RE, Reynolds TH, Supiano MA: Renal hemodynamic and blood pressure responses to dietary sodium are associated with the t-786c endothelial nitric oxide synthase gene. Physiological Research 56:393-401, 2007.

    Ness KK, Baker KS, Dengel DR, Youngren N, Sibley S, Mertens AC, Gurney JG: Body composition, muscle strength deficits, and mobility limitations in adult survivors of childhood acute lymphoblastic leukemia. Pediatric Blood & Cancer 49:975-981, 2007.

    Borer KT, Fogleman K, Gross MM, La New JM, Dengel DR: Walking intensity for postmenopausal bone mineral preservation and accrual. Bone 41:713-721, 2007.

    Huck CJ, Bronas UG, Williamson EB, Draheim CC, Duprez DA, Dengel DR: Noninvasive measurements of arterial stiffness: Repeatability and interrelationships with endothelial function and arterial morphology measures. Journal of Vascular Health 3(3):343-349, 2007.

    Olson TP, Dengel DR, Leon AS, Schmitz KH: I Changes in inflammatory biomarkers following one-year of moderate resistance training in overweight women. International Journal of Obesity 31:996-1003, 2007.

    Scott RM, Kaufman CL, Dengel DR: The Impact of Chiropractic Adjustments on Intracranial Blood Flow:Kaufman CL, Kaiser DR, Steinberger J, Dengel DR: Relationships between heart rate variability, vascular function, and adiposity in children. Clinical Autonomic Research 17(3):165-171, 2007.

    Kelly AS, Steinberger J, Olson TP, Dengel DR. In the absence of weight loss, exercise training does not improve adipokines or oxidative stress in overweight children. Metabolism 56:1005-1009, 2007.

    Kaufman C, Kelly AS, Kaiser DR, Steinberger J, Dengel DR: Aerobic-exercise training improves ventilatory efficiency in overweight children. Pediatric Exercise Science 19:82-92, 2007.

    Reynolds TH, Supiano MA, Dengel DR: Differences in Glucose Clearance: The effects of insulin and resistance training on arm and leg glucose clearance in older hypertensive individuals. Journal of Applied Physiology 102:985-991, 2007.

    Dengel DR, Kelly AS, Steinberger J, Sinaiko AR: Effect of oral glucose loading on endothelial function in normal and overweight children. Clinical Science 112(9):493-498, 2007.

    Parker ED, Schmitz KH, Jacobs DR, Dengel DR, Schreiner PJ: Physical activity in young adults and incident hypertension over 15 years of follow-up: The CARDIA study. American Journal of Public Health 97:703-709, 2007.

    Kaufman CL, Kaiser DR, Steinberger J, Kelly AS, Dengel DR: Relationships of Cardiac Autonomic Function with Metabolic Abnormalities in Childhood Obesity. Obesity 15:1164-1171, 2007.

     

  2. Dengel DR, Pratley RE, Hagberg JM, Rogus EM, Goldberg AP: Distinct effects of aerobic exercise training and weight loss on glucose homeostasis in obese sedentary men. Journal of Applied Physiology 81:318-325, 1996.

  3. Dengel DR, Galecki AT, Hagberg JM, Pratley RE:  The independent and combined effects of weight loss and aerobic exercise on blood pressure and oral glucose tolerance in older men. American Journal of Hypertension 11:1405-1412, 1998.

  4.  

    Dengel DR, Brown MD, Ferrell RE, Reynolds TH, Supiano MA: Exercise-induced enhancements in insulin action are associated with ACE gene polymorphisms in older hypertensives. Physiological Genomics 11:73-80, 2002.

  5. Kelly AS, Wetzsteon RJ, Kaiser DR, Steinberger J, Bank AJ, Dengel DR: Inflammation, insulin, and endothelial function in overweight children and adolescents: the role of exercise. Journal of Pediatrics 145(6):731-736, 2004.

  6. Dengel DR, Ness KK, Glasser SP, Williamson EB, Baker KS, Gurney JG:  Endothelial Function In Young Adult Survivors Of Childhood Acute Lymphoblastic Leukemia.  Journal of Pediatric Hematology Oncology 30:20-25, 2008.


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Last modified on 7/25/2013