Andrew Nauertz is a senior at the University of Saint Thomas - St. Paul majoring in biology and minoring in chemistry. His research interests lie in viruses specifically human immunodeficiency virus (HIV) and herpes simplex virus. Mr. Nauertz plans on attending medical school and pursuing a Ph.D. in virology as well.
My goal is to practice medicine and treat patients with the same amount of respect and empathy that my own doctor has shown my mother and myself. I want to be involved in conducting medical research and integrate my discoveries into everyday patient care.
Antiviral Properties of Natural Extracts Against Feline Calici Virus, a Surrogate to Norovirus
Abstract: Natural extracts have been found to exhibit antibacterial, antifungal, and antiviral effects. Norovirus is an enteric pathogen which has no known cure or vaccination making it a prime candidate to test the antiviral properties of various natural extracts: cloves, fenugreek, garlic, ginger, habanero pepper, jalapeno pepper, and onion. However, norovirus cannot be grown in tissue cultures which is why we used feline calici virus as a surrogate to human norovirus. Feline calici virus grows on Crandall-Reese kidney cells, and to determine a non lethal dose cytoxicity assays were run for all extracts. We then tested the antiviral properties of the extracts using cytopathogenicity (CPE) assays. Using Karber's method we calculated the tissue culture infectious dose (TCID50). The initial virus titer came to be 107.5 TCID50 per mL. Our findings did not show any of the extracts to have antiviral properties as the virus titer decreased by a maximum of one Log. Download poster. [PDF]
Sagar M. Goyal i is currently a virologist with the Department of Veterinary Population Medicine at the University of Minnesota. He received his Ph.D. in veterinary virology in 1972 from Haryana Agricultural University in Hissar, India. His research interests revolve around the pathogenesis and control of viral infections in livestock and poultry, and the development of methods for the detection and prevention of human and animal viruses in food, water, animals, and the environment. Dr. Goyal has published over 300 scientific articles and has also won the Pfizer Award for research excellence in veterinary medicine in 2005. This is his second year as a McNair mentor.